A powdered probiotic + powerful anti-anxiety supplement for stressed pets and people. Has been shown to regrow hair in stressed individuals. Can be added to canned or dry pet food or juice and smoothies for people. No hot liquids. This is a concentrated probiotic and must be started at a fraction of the final dose to prevent diarrhea. Effectiveness increases with increasing dose, and may take up to a month to see visable differences. Pets 1 rounded teaspoon, once or twice a day for 30 lb. dog. Increase or decrease dose depending on weight and stress level of pet. MSE Calm Defense is more effective in stressed individuals. Stress level may be estimated by changes in appetite, excitability, barking, sleep habits, hair loss, and behavior. An animal nutritionist can assist you with this and all our probiotics, please contact Lark Burnham at lark@naturs-way.com for help. Ingredients: A proprietary blend of Lactobacillus acidophilus, L. casei, Streplococcus faecium, Saccharomyces cerevisiae, and Bifidobacterium sp., plus l-tryptophan.